Lactate normalization within 6 hours of bundle therapy and 24 hours of delayed achievement were associated with 28-day mortality in septic shock patients

This study evaluated the prognostic ability of lactate normalization achieved within 6 and 24 h from septic shock recognition. Data from a septic shock registry from October 2015 to February 2017 were reviewed. The study included 2,102 eligible septic shock patients to analyze the prognostic ability...

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Veröffentlicht in:	PloS one 2019-06, Vol.14 (6), p.e0217857-e0217857
Hauptverfasser:	Ryoo, Seung Mok, Ahn, Ryeok, Shin, Tae Gun, Jo, You Hwan, Chung, Sung Phil, Beom, Jin Ho, Choi, Sung-Hyuk, Yoon, Young-Hoon, Ko, Byuk Sung, Lee, Hui Jai, Suh, Gil Joon, Kim, Won Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis Biology and Life Sciences Confidence intervals Control Emergency medical care Female Health risk assessment Hospitals Humans Intensive care Lactic acid Lactic Acid - metabolism Logistic regression Male Medical research Medical schools Medicine Medicine and Health Sciences Mortality Multivariate Analysis Patient outcomes Physical Sciences Regression analysis Sepsis Septic shock Shock Shock, Septic - mortality Shock, Septic - therapy Statistical analysis Therapeutic applications Therapy Time Factors
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Zusammenfassung:	This study evaluated the prognostic ability of lactate normalization achieved within 6 and 24 h from septic shock recognition. Data from a septic shock registry from October 2015 to February 2017 were reviewed. The study included 2,102 eligible septic shock patients to analyze the prognostic ability of lactate normalization, defined as a follow-up lactate level
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0217857