Sensitivity and characteristics associated with positive QuantiFERON-TB Gold-Plus assay in children with confirmed tuberculosis

Although QuantiFERON-TB Gold Plus (QFT-Plus), a new interferon-gamma release assay, has shown good performance in adults, little data is available in children. De-identified data from TB-suspected patients age

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Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2019-03, Vol.14 (3), p.e0213304-e0213304
Hauptverfasser:	Nguyen, Duc T, Phan, Ha, Trinh, Trang, Nguyen, Hang, Doan, Ha, Pham, Nam, Nguyen, Hung, Nguyen, Hanh, Nguyen, Hung V, Le, Hoi V, Nguyen, Nhung, Graviss, Edward A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adults Assaying Biological Assay - methods Biological response modifiers Biology and Life Sciences Child Child, Preschool Children Collaboration Female Gold HIV Hospitals Human immunodeficiency virus Humans Identification methods Infant Infant, Newborn Infections Infectious diseases Interferon Interferon gamma release tests Interferon-gamma Release Tests - methods Lungs Male Mass Screening Medical diagnosis Medicine and Health Sciences Mycobacterium tuberculosis - isolation & purification Patients Pediatric diseases Pediatric research Pediatrics People and Places Peptides Prevalence Regression analysis ROC Curve Sensitivity Subgroups Systematic review Tuberculosis Tuberculosis - diagnosis Tuberculosis - epidemiology Tuberculosis - microbiology Vietnam - epidemiology γ-Interferon
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Beschreibung
Zusammenfassung:	Although QuantiFERON-TB Gold Plus (QFT-Plus), a new interferon-gamma release assay, has shown good performance in adults, little data is available in children. De-identified data from TB-suspected patients age
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0213304