Prognostic significance of preoperative CT findings in patients with advanced gastric cancer who underwent curative gastrectomy

Preoperative therapy has gained wide interest in advanced gastric cancer patients due to its potential advantages of improved disease control. Selection of high risk patients based on preoperative staging is crucial to choose the candidates for neoadjuvant therapy. Our institutional review board app...

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Veröffentlicht in:PloS one 2018-08, Vol.13 (8), p.e0202207-e0202207
Hauptverfasser: Park, Chae Jung, Seo, Nieun, Hyung, Woo Jin, Koom, Woong Sub, Kim, Hyo Song, Kim, Myeong-Jin, Lim, Joon Seok
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Sprache:eng
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Zusammenfassung:Preoperative therapy has gained wide interest in advanced gastric cancer patients due to its potential advantages of improved disease control. Selection of high risk patients based on preoperative staging is crucial to choose the candidates for neoadjuvant therapy. Our institutional review board approved this retrospective study and waived the requirement for patient consent. We searched 394 advanced gastric cancer patients (pT2-4) who underwent curative resection in 2010 without neoadjuvant therapies. Two abdominal radiologists independently reviewed the preoperative CT including tumor depth on CT (CT-tumor depth), which was categorized as follows: intramural, minimal extramural(
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0202207