Cryptococcal antigen positivity combined with the percentage of HIV-seropositive samples with CD4 counts <100 cells/μl identifies districts in South Africa with advanced burden of disease

Cryptococcal meningitis (CM) is an opportunistic fungal disease with a high mortality among HIV-positive patients with severe immunosuppression (CD4 count

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Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2018-06, Vol.13 (6), p.e0198993-e0198993
Hauptverfasser:	Coetzee, Lindi-Marie, Cassim, Naseem, Sriruttan, Charlotte, Mhlanga, Mabatho, Govender, Nelesh P, Glencross, Deborah Kim
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS Antigens Antigens, Fungal - immunology Antigens, Fungal - metabolism Antimicrobial agents Biology and Life Sciences CD4 antigen CD4 Lymphocyte Count Cryptococcosis - complications Cryptococcosis - diagnosis Cryptococcosis - epidemiology Cryptococcosis - microbiology Cryptococcus - immunology Data warehouses Disease control Drug resistance Drug therapy Epidemiology Fungal diseases Fungal infections Health sciences Hematology HIV HIV - immunology HIV Infections - complications HIV Infections - diagnosis HIV Infections - epidemiology HIV Infections - virology Human immunodeficiency virus Humans Identification methods Immune Tolerance Immunosuppression Infections Infectious diseases Mass Screening Medical screening Medicine and Health Sciences Meningitis Mortality People and places Pilot Projects Research and Analysis Methods South Africa - epidemiology
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Beschreibung
Zusammenfassung:	Cryptococcal meningitis (CM) is an opportunistic fungal disease with a high mortality among HIV-positive patients with severe immunosuppression (CD4 count
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0198993