Cholelithiasis and choledocholithiasis in children; risk factors for development

To compare anthropometric data (body mass index [BMI]) in patients without lithiasis to patients with symptomatic simple cholelithiasis or choledocholithiasis. We retrospectively reviewed data from 147 patients undergoing laparoscopic cholecystectomy between 2001-2015. Complete growth data from 98 p...

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Veröffentlicht in:PloS one 2018-05, Vol.13 (5), p.e0196475-e0196475
Hauptverfasser: Frybova, Barbora, Drabek, Jiri, Lochmannova, Jindra, Douda, Ladislav, Hlava, Stepan, Zemkova, Daniela, Mixa, Vladimir, Kyncl, Martin, Zeman, Lubos, Rygl, Michal, Keil, Radan
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Sprache:eng
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Zusammenfassung:To compare anthropometric data (body mass index [BMI]) in patients without lithiasis to patients with symptomatic simple cholelithiasis or choledocholithiasis. We retrospectively reviewed data from 147 patients undergoing laparoscopic cholecystectomy between 2001-2015. Complete growth data from 98 patients was compared with anthropometric data from the population of the Czech Republic and a control group (BMI of 100 consecutive patients without biliary stones in abdominal ultrasound who were admitted to a surgical department for suspected appendicitis). The BMI of 75 children with simple cholelithiasis and 23 with choledocholithiasis was compared to the standard Czech pediatric population and to the control group. The median age (simple cholelithiasis and choledocholithiasis) was 16 years, and 35 patients (24%) had a family history of gallstones. Types of lithiasis included multiple (n = 120), solitary (n = 11), and sludge (n = 10). Five cases had polyps and one had gallbladder dysplasia. Patients with simple cholelithiasis had significantly higher BMI compared to the control group without cholelithiasis (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0196475