Prevalence of metabolic syndrome and its risk factors in Kerala, South India: Analysis of a community based cross-sectional study

Coronary Artery Disease (CAD) is a leading cause of death and disability in Kerala, India. Metabolic syndrome (MS) is a constellation of established risk factors for CAD. We aimed to estimate the prevalence of MS and evaluate the association between MS and CAD using a community-based sample populati...

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Veröffentlicht in:PloS one 2018-03, Vol.13 (3), p.e0192372-e0192372
Hauptverfasser: Harikrishnan, S, Sarma, Smitha, Sanjay, G, Jeemon, P, Krishnan, M N, Venugopal, K, Mohanan, P P, Jeyaseelan, L, Thankappan, K R, Zachariah, G
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Sprache:eng
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Zusammenfassung:Coronary Artery Disease (CAD) is a leading cause of death and disability in Kerala, India. Metabolic syndrome (MS) is a constellation of established risk factors for CAD. We aimed to estimate the prevalence of MS and evaluate the association between MS and CAD using a community-based sample population. A cross-sectional community based survey was conducted in urban and rural areas of Kerala in 2011. We included 5063 individuals for analysis. Age standardized prevalence of MS, associated diagnoses (hypertension, diabetes and hypercholesterolemia) and other potential risk factors were assessed for men and women in both urban and rural locations. Univariate and multivariate logistic regression models were developed to identify participant characteristics that are associated with MS. After standardization for age and adjustment for sex and urban-rural distribution, the prevalence of metabolic syndrome in Kerala was 24%, 29% and 33% for the NCEP ATP III, IDF and AHA/NHLBI Harmonization definitions, respectively. The mean (SD) age of the participants was 51 (14) years, and 60% were women. Women had a higher prevalence of MS than men (28% versus 20% for ATP III, p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0192372