Clinical predictors of outcome in patients with inflammatory dilated cardiomyopathy

The study objectives were to identify predictors of outcome in patients with inflammatory dilated cardiomyopathy (DCMi). From 2004 to 2008, 55 patients with biopsy-proven DCMi were identified and followed up for 58.2±19.8 months. Predictors of outcome were identified in a multivariable analysis with...

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Veröffentlicht in:PloS one 2017-12, Vol.12 (12), p.e0188491-e0188491
Hauptverfasser: Karatolios, Konstantinos, Holzendorf, Volker, Hatzis, George, Tousoulis, Dimitrios, Richter, Anette, Schieffer, Bernhard, Pankuweit, Sabine
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Sprache:eng
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Zusammenfassung:The study objectives were to identify predictors of outcome in patients with inflammatory dilated cardiomyopathy (DCMi). From 2004 to 2008, 55 patients with biopsy-proven DCMi were identified and followed up for 58.2±19.8 months. Predictors of outcome were identified in a multivariable analysis with a Cox proportional hazards analysis. The primary endpoint was a composite of death, heart transplantation and hospitalization for heart failure or ventricular arrhythmias. For the primary endpoint, a QTc interval >440msec (HR 2.84; 95% CI 1.03-7.87; p = 0.044), a glomerular filtration rate (GFR)
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0188491