Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel

Proteins, widely studied as potential biomarkers, play important roles in numerous physiological functions and diseases. Genetic variation may modulate corresponding protein levels and point to the role of these variants in disease pathophysiology. Effects of individual single nucleotide polymorphis...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-07, Vol.8 (7), p.e70269-e70269
Hauptverfasser:	Kim, Sungeun, Swaminathan, Shanker, Inlow, Mark, Risacher, Shannon L, Nho, Kwangsik, Shen, Li, Foroud, Tatiana M, Petersen, Ronald C, Aisen, Paul S, Soares, Holly, Toledo, Jon B, Shaw, Leslie M, Trojanowski, John Q, Weiner, Michael W, McDonald, Brenna C, Farlow, Martin R, Ghetti, Bernardino, Saykin, Andrew J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Aged Aged, 80 and over Aging Alzheimer Disease - blood Alzheimer Disease - genetics Alzheimer's disease Angiotensin Angiotensinogen Apolipoproteins E - blood Apolipoproteins E - genetics Bioindicators Bioinformatics Biology Biomarkers Blood pressure Blood proteins Chromosomes Complement C3b Inactivator Proteins - analysis Complement C3b Inactivator Proteins - genetics Complement factor H Data processing Disease Disease control Elderly Female Genes Genetic aspects Genetic diversity Genetics Genome-wide association studies Genome-Wide Association Study Genomes Genomics Haplotypes Humans Hypertension Interleukin Interleukin 6 Laboratories Linear Models Linkage disequilibrium Male Medical imaging Medical research Medicine Middle Aged Multiplexing Neuroimaging Neurology Older people Pathology Peptidyl-dipeptidase A Physicians Plasma Polymorphism, Single Nucleotide Proteins Proteomics Regression analysis Single nucleotide polymorphisms Single-nucleotide polymorphism Studies Variation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!