Spirometry, questionnaire and electronic medical record based COPD in a population survey: Comparing prevalence, level of agreement and associations with potential risk factors

COPD-diagnosis is confirmed by post-bronchodilator (BD) spirometry. However, epidemiological studies often rely on pre-BD spirometry, self-reports, or medical records. This population-based study aims to determine COPD-prevalence based on four different operational definitions and their level of agr...

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Veröffentlicht in:PloS one 2017-03, Vol.12 (3), p.e0171494-e0171494
Hauptverfasser: Borlée, Floor, Yzermans, C Joris, Krop, Esmeralda, Aalders, Bernadette, Rooijackers, Jos, Zock, Jan-Paul, van Dijk, Christel E, Maassen, Catharina B M, Schellevis, François, Heederik, Dick, Smit, Lidwien A M
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Sprache:eng
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Zusammenfassung:COPD-diagnosis is confirmed by post-bronchodilator (BD) spirometry. However, epidemiological studies often rely on pre-BD spirometry, self-reports, or medical records. This population-based study aims to determine COPD-prevalence based on four different operational definitions and their level of agreement, and to compare associations between COPD-definitions and risk factors. COPD-prevalence in 1,793 adults from the general Dutch population (aged 18-70 years) was assessed based on self-reported data, Electronic Medical Records (EMR), and post-BD spirometry: using the FEV1/FVC below the lower limit of normal (LLN) and GOLD fixed cut-off (FEV1/FVC
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0171494