Increased Symmetric Dimethylarginine Level Is Associated with Worse Hospital Outcomes through Altered Left Ventricular Ejection Fraction in Patients with Acute Myocardial Infarction

We aimed to investigate whether SDMA- symmetric dimethylarginine -the symmetrical stereoisomer of ADMA- might be a marker of left ventricular function in AMI. Asymmetric dimethylarginine (ADMA) has been implicated in the prognosis after acute myocardial infarction (AMI) and heart failure (HF). Cross...

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Veröffentlicht in:PloS one 2017-01, Vol.12 (1), p.e0169979-e0169979
Hauptverfasser: Lorin, Julie, Guilland, Jean-Claude, Stamboul, Karim, Guenancia, Charles, Cottin, Yves, Rochette, Luc, Vergely, Catherine, Zeller, Marianne
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Sprache:eng
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Zusammenfassung:We aimed to investigate whether SDMA- symmetric dimethylarginine -the symmetrical stereoisomer of ADMA- might be a marker of left ventricular function in AMI. Asymmetric dimethylarginine (ADMA) has been implicated in the prognosis after acute myocardial infarction (AMI) and heart failure (HF). Cross sectional prospective study from 487 consecutive patients hospitalized 2, and death. Patients were analysed based on SDMA tertiles. Sex, diabetes, dyslipidemia, and prior MI were similar for all tertiles. In contrast, age and hypertension increased across the tertiles (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0169979