Viral Manipulation of Host Inhibitory Receptor Signaling for Immune Evasion
Eugenia Z. Ong Affiliation: Experimental Therapeutics Centre, Agency for Science, Technology, and Research, Singapore Kuan Rong Chan Affiliation: Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore Eng Eong Ooi * E-mail: engeong.ooi@duke-nus.edu.sg Affiliations Programme in...
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| Veröffentlicht in: | PLoS pathogens 2016-09, Vol.12 (9), p.e1005776-e1005776 |
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| container_title | PLoS pathogens |
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| creator | Ong, Eugenia Z Chan, Kuan Rong Ooi, Eng Eong |
| description | Eugenia Z. Ong Affiliation: Experimental Therapeutics Centre, Agency for Science, Technology, and Research, Singapore Kuan Rong Chan Affiliation: Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore Eng Eong Ooi * E-mail: engeong.ooi@duke-nus.edu.sg Affiliations Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore-MIT Alliance in Research and Technology, Infectious Diseases Interdisciplinary Group, SingaporeCitation: Ong EZ, Chan KR, Ooi EE (2016) Viral Manipulation of Host Inhibitory Receptor Signaling for Immune Evasion. [...]viruses that cause chronic diseases in humans utilize inhibitory signaling to impose T cell exhaustion, which greatly hampers response to disease treatment. |
| doi_str_mv | 10.1371/journal.ppat.1005776 |
| format | Article |
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Ong Affiliation: Experimental Therapeutics Centre, Agency for Science, Technology, and Research, Singapore Kuan Rong Chan Affiliation: Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore Eng Eong Ooi * E-mail: engeong.ooi@duke-nus.edu.sg Affiliations Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore-MIT Alliance in Research and Technology, Infectious Diseases Interdisciplinary Group, SingaporeCitation: Ong EZ, Chan KR, Ooi EE (2016) Viral Manipulation of Host Inhibitory Receptor Signaling for Immune Evasion. 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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Ong EZ, Chan KR, Ooi EE (2016) Viral Manipulation of Host Inhibitory Receptor Signaling for Immune Evasion. PLoS Pathog 12(9): e1005776. doi:10.1371/journal.ppat.1005776</rights><rights>2016 Ong et al 2016 Ong et al</rights><rights>2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Ong EZ, Chan KR, Ooi EE (2016) Viral Manipulation of Host Inhibitory Receptor Signaling for Immune Evasion. 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Ong Affiliation: Experimental Therapeutics Centre, Agency for Science, Technology, and Research, Singapore Kuan Rong Chan Affiliation: Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore Eng Eong Ooi * E-mail: engeong.ooi@duke-nus.edu.sg Affiliations Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore-MIT Alliance in Research and Technology, Infectious Diseases Interdisciplinary Group, SingaporeCitation: Ong EZ, Chan KR, Ooi EE (2016) Viral Manipulation of Host Inhibitory Receptor Signaling for Immune Evasion. 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Ong Affiliation: Experimental Therapeutics Centre, Agency for Science, Technology, and Research, Singapore Kuan Rong Chan Affiliation: Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore Eng Eong Ooi * E-mail: engeong.ooi@duke-nus.edu.sg Affiliations Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore-MIT Alliance in Research and Technology, Infectious Diseases Interdisciplinary Group, SingaporeCitation: Ong EZ, Chan KR, Ooi EE (2016) Viral Manipulation of Host Inhibitory Receptor Signaling for Immune Evasion. [...]viruses that cause chronic diseases in humans utilize inhibitory signaling to impose T cell exhaustion, which greatly hampers response to disease treatment.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>27584579</pmid><doi>10.1371/journal.ppat.1005776</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Animals Biology and life sciences Cellular signal transduction Chronic illnesses Colleges & universities Cytotoxicity Homeostasis Host-Pathogen Interactions - immunology Humans Immune Evasion - immunology Immune response Immune system Immunity, Innate - immunology Immunology Infections Infectious diseases Kinases Ligands Lymphocytes Medical treatment Medicine and health sciences Microbiology Pathogenesis Pearls Phosphatase Physiological aspects Proteins Public health Viral infections Virus diseases Virus Diseases - immunology Viruses |
| title | Viral Manipulation of Host Inhibitory Receptor Signaling for Immune Evasion |
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