Modeling of Experimental Data Supports HIV Reactivation from Latency after Treatment Interruption on Average Once Every 5-8 Days

The correlation between growth rate and time-to-detection in cohort 3 was in fact positive (r = 0.029, p = 0.9) despite an expected negative correlation. The fourth estimate comes from Hill et al.'s own previous work[4] but is derived directly from the estimate of reference [3] (see S1 Methods). [...]the evidence for a reactivation rate of 4 per day hinges upon reference [3]'s use of a 13-parameter model of time to drug resistance, in which many of the input parameters are described as "roughly based on the literature"[3].