The Janus-Face of Bacteriophages across Human Body Habitats

A role of phages in periodontal disease has also recently been demonstrated [23,24]. Since periodontal disease is associated with dysbiosis, it may prove to function as a tractable model system to study the involvement of phage populations in mixed infectious diseases [25,26]. Unlike most other phages, P. acnes phages are characterized by a conspicuous lack of genetic diversity [62]. Because of their genome stability along with their relatively broad host range, the suitability of P. acnes phages for anti-acne treatment has been proposed [62,63].