Fungal Peritonitis: Underestimated Disease in Critically Ill Patients with Liver Cirrhosis and Spontaneous Peritonitis

Spontaneous peritonitis, especially spontaneous fungal peritonitis (SFP), is an important and potentially fatal complication in patients with endstage liver disaese. We evaluated potential risk factors, microbiological findings, and outcome of patients with SFP compared to spontaneous bacterial peri...

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Veröffentlicht in:	PloS one 2016-07, Vol.11 (7), p.e0158389-e0158389
Hauptverfasser:	Lahmer, Tobias, Brandl, Andreas, Rasch, Sebastian, Schmid, Roland M, Huber, Wolfgang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Analysis Antibiotics Bacterial infections Biology and Life Sciences Candida Candida albicans Candida glabrata Candida krusei Candidiasis - drug therapy Candidiasis - etiology Candidiasis - mortality Cirrhosis Complications and side effects Critical Illness Critically ill persons Cross Infection - drug therapy Cross Infection - microbiology Cross Infection - mortality Female Fungal infections Fungi Health aspects Hepatitis Hospitals Humans Infectious diseases Liver Liver cirrhosis Liver Cirrhosis - complications Liver Cirrhosis - drug therapy Liver Cirrhosis - microbiology Liver Cirrhosis - mortality Liver diseases Male Medical personnel Medical records Medicine and Health Sciences Middle Aged Mortality Nosocomial infection Patients People and Places Peritonitis Peritonitis - drug therapy Peritonitis - etiology Peritonitis - microbiology Peritonitis - mortality Permeability Physicians Research and Analysis Methods Retrospective Studies Risk analysis Risk factors Thoracic surgery
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Zusammenfassung:	Spontaneous peritonitis, especially spontaneous fungal peritonitis (SFP), is an important and potentially fatal complication in patients with endstage liver disaese. We evaluated potential risk factors, microbiological findings, and outcome of patients with SFP compared to spontaneous bacterial peritonitis (SBP) in critically ill patients. Retrospective analyses of critically ill patients with suspected spontaneous peritonitis. Out of 205 patients, 20 (10%) had SFP, 28 (14%) had SBP, 48 (24%) had peritonitis without microbiological findings (SP) and 109 (52%) had no-peritonitis (NP). APACHE II and SOFA score were significantly higher in patients with SFP (26; 22-28; p
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0158389