Seroprevalence and Risk Factors of Varicella Zoster Infection in Iranian Adolescents: A Multilevel Analysis; The CASPIAN-III Study

The objective of this study was to evaluate the varicella zoster virus (VZV) immunity in Iranian adolescents. It was conducted as a primary study for vaccine implementation, and to investigate the association of climatic and socioeconomic factors with the epidemiology of this infection. In this cros...

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Veröffentlicht in:PloS one 2016-06, Vol.11 (6), p.e0158398-e0158398
Hauptverfasser: Hoseini, Shervin Ghaffari, Kelishadi, Roya, Kasaeian, Amir, Ataei, Behrooz, Yaran, Majid, Motlagh, Mohammad Esmaeil, Heshmat, Ramin, Ardalan, Gelayol, Safari, Omid, Qorbani, Mostafa, Mostafavi, Seyed Naseredin
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Sprache:eng
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Zusammenfassung:The objective of this study was to evaluate the varicella zoster virus (VZV) immunity in Iranian adolescents. It was conducted as a primary study for vaccine implementation, and to investigate the association of climatic and socioeconomic factors with the epidemiology of this infection. In this cross- sectional study, anti VZV antibodies were measured in serum samples obtained in a national school-based health survey (CASPIAN- III). Association of demographic, socio-economic, and climate of the living region with the frequency of VZV was investigated by multivariate multilevel analysis. Overall, sera of 2753 individuals aged 10-18 were tested for VZV antibodies, from those 87.4% were positive. The prevalence was statistically different in four socio-geographic regions (P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0158398