Maternal Whole Blood Gene Expression at 18 and 28 Weeks of Gestation Associated with Spontaneous Preterm Birth in Asymptomatic Women

Maternal Whole Blood Gene Expression at 18 and 28 Weeks of Gestation Associated with Spontaneous Preterm Birth in Asymptomatic Women

The heterogeneity of spontaneous preterm birth (SPTB) requires an interdisciplinary approach to determine potential predictive risk factors of early delivery. The aim of this study was to investigate maternal whole blood gene expression profiles associated with spontaneous preterm birth (SPTB,

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Veröffentlicht in:PloS one 2016-06, Vol.11 (6), p.e0155191-e0155191
Hauptverfasser: Heng, Yujing J, Pennell, Craig E, McDonald, Sheila W, Vinturache, Angela E, Xu, Jingxiong, Lee, Mary W F, Briollais, Laurent, Lyon, Andrew W, Slater, Donna M, Bocking, Alan D, de Koning, Lawrence, Olson, David M, Dolan, Siobhan M, Tough, Suzanne C, Lye, Stephen J
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Analysis
Anemia
Area Under Curve
Babies
Biology and Life Sciences
Birth
Blood
Childbirth & labor
Cytokines
Demography
Departments
DNA microarrays
Female
Gene expression
Gene Expression Regulation, Developmental
Gestation
Gynecology
Health aspects
Health sciences
Hospitals
Humans
Labor, Obstetric
Mathematical models
Medicine
Medicine and Health Sciences
Models, Genetic
Multivariate Analysis
Obstetrics
Physiology
Population studies
Pregnancy
Pregnant women
Premature birth
Premature Birth - blood
Premature Birth - genetics
Prenatal diagnosis
Public health
Real-Time Polymerase Chain Reaction
Reproducibility of Results
Research and Analysis Methods
Ribonucleic acid
Risk analysis
Risk factors
RNA
Sensitivity
Sensitivity enhancement
Smooth muscle
Subgroups
Systematic review
Womens health
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Zusammenfassung:The heterogeneity of spontaneous preterm birth (SPTB) requires an interdisciplinary approach to determine potential predictive risk factors of early delivery. The aim of this study was to investigate maternal whole blood gene expression profiles associated with spontaneous preterm birth (SPTB,
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0155191