Quantifying the Epidemiological Impact of Vector Control on Dengue

Results will provide a benchmark for subsequent trials in which combinations of interventions are assessed.\n Ignoring human movement during study design considerations would require an artificial increase in the expected effectiveness to achieve adequate power because every individual in a treatmen...

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Veröffentlicht in:PLoS neglected tropical diseases 2016-05, Vol.10 (5), p.e0004588
Hauptverfasser: Reiner, Jr, Robert C, Achee, Nicole, Barrera, Roberto, Burkot, Thomas R, Chadee, Dave D, Devine, Gregor J, Endy, Timothy, Gubler, Duane, Hombach, Joachim, Kleinschmidt, Immo, Lenhart, Audrey, Lindsay, Steven W, Longini, Ira, Mondy, Mathias, Morrison, Amy C, Perkins, T Alex, Vazquez-Prokopec, Gonzalo, Reiter, Paul, Ritchie, Scott A, Smith, David L, Strickman, Daniel, Scott, Thomas W
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container_issue 5
container_start_page e0004588
container_title PLoS neglected tropical diseases
container_volume 10
creator Reiner, Jr, Robert C
Achee, Nicole
Barrera, Roberto
Burkot, Thomas R
Chadee, Dave D
Devine, Gregor J
Endy, Timothy
Gubler, Duane
Hombach, Joachim
Kleinschmidt, Immo
Lenhart, Audrey
Lindsay, Steven W
Longini, Ira
Mondy, Mathias
Morrison, Amy C
Perkins, T Alex
Vazquez-Prokopec, Gonzalo
Reiter, Paul
Ritchie, Scott A
Smith, David L
Strickman, Daniel
Scott, Thomas W
description Results will provide a benchmark for subsequent trials in which combinations of interventions are assessed.\n Ignoring human movement during study design considerations would require an artificial increase in the expected effectiveness to achieve adequate power because every individual in a treatment cluster will be predicted to have the "maximum" effect. Insights from such trials will help guide the scaling up of effective dengue control strategies, whether vector control alone or in combination with vaccines, and will be applicable to other Ae. aegypti-borne viral infections of current public health concern, such as chikungunya and Zika viruses.
doi_str_mv 10.1371/journal.pntd.0004588
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subjects Aedes - physiology
Aedes - virology
Animals
Biology and Life Sciences
Dengue - epidemiology
Dengue - prevention & control
Dengue - transmission
Dengue - virology
Dengue fever
Disease
Earth Sciences
Epidemiology
Evaluation
Funding
Humans
Illnesses
Infections
Insecticides
Intervention
Medicine and Health Sciences
Methods
Mortality
Mosquito Control
Mosquito Vectors - physiology
Mosquito Vectors - virology
Mosquitoes
Pathogens
Planning
Policy Platform
Prevention
Public health
Quantitative research
Social Sciences
Studies
Tropical diseases
Vaccines
Vector control
Vectors (Biology)
Viral infections
Viruses
title Quantifying the Epidemiological Impact of Vector Control on Dengue
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