The Burden of Cryptosporidium Diarrheal Disease among Children < 24 Months of Age in Moderate/High Mortality Regions of Sub-Saharan Africa and South Asia, Utilizing Data from the Global Enteric Multicenter Study (GEMS)

The importance of Cryptosporidium as a pediatric enteropathogen in developing countries is recognized. Data from the Global Enteric Multicenter Study (GEMS), a 3-year, 7-site, case-control study of moderate-to-severe diarrhea (MSD) and GEMS-1A (1-year study of MSD and less-severe diarrhea [LSD]) wer...

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Veröffentlicht in:	PLoS neglected tropical diseases 2016-05, Vol.10 (5), p.e0004729
Hauptverfasser:	Sow, Samba O, Muhsen, Khitam, Nasrin, Dilruba, Blackwelder, William C, Wu, Yukun, Farag, Tamer H, Panchalingam, Sandra, Sur, Dipika, Zaidi, Anita K M, Faruque, Abu S G, Saha, Debasish, Adegbola, Richard, Alonso, Pedro L, Breiman, Robert F, Bassat, Quique, Tamboura, Boubou, Sanogo, Doh, Onwuchekwa, Uma, Manna, Byomkesh, Ramamurthy, Thandavarayan, Kanungo, Suman, Ahmed, Shahnawaz, Qureshi, Shahida, Quadri, Farheen, Hossain, Anowar, Das, Sumon K, Antonio, Martin, Hossain, M Jahangir, Mandomando, Inacio, Nhampossa, Tacilta, Acácio, Sozinho, Omore, Richard, Oundo, Joseph O, Ochieng, John B, Mintz, Eric D, O'Reilly, Ciara E, Berkeley, Lynette Y, Livio, Sofie, Tennant, Sharon M, Sommerfelt, Halvor, Nataro, James P, Ziv-Baran, Tomer, Robins-Browne, Roy M, Mishcherkin, Vladimir, Zhang, Jixian, Liu, Jie, Houpt, Eric R, Kotloff, Karen L, Levine, Myron M
Format:	Artikel
Sprache:	eng
Schlagworte:	Afghanistan - epidemiology Africa South of the Sahara - epidemiology Asia - epidemiology Biology and Life Sciences Care and treatment Case-Control Studies Child, Preschool Children Cost of Illness Cryptosporidiosis - epidemiology Cryptosporidiosis - mortality Cryptosporidiosis - parasitology Cryptosporidium Cryptosporidium - classification Cryptosporidium - genetics Cryptosporidium - immunology Cryptosporidium - isolation & purification Data Mining - methods Developing countries Developing Countries - economics Developing Countries - statistics & numerical data Diagnosis Diarrea Diarrhea Diarrhea - epidemiology Diarrhea - mortality Diarrhea - parasitology Feces - parasitology Female Gastrointestinal Diseases - epidemiology Gastrointestinal Diseases - mortality Gastrointestinal Diseases - parasitology Genotypes Health aspects Humans Immunoassay Incidence India - epidemiology Infant Infant, Newborn Infants LDCs Male Medicine and Health Sciences Mortality People and Places Polymerase Chain Reaction Protozoa Risk factors Tropical diseases Vaccines
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Zusammenfassung:	The importance of Cryptosporidium as a pediatric enteropathogen in developing countries is recognized. Data from the Global Enteric Multicenter Study (GEMS), a 3-year, 7-site, case-control study of moderate-to-severe diarrhea (MSD) and GEMS-1A (1-year study of MSD and less-severe diarrhea [LSD]) were analyzed. Stools from 12,110 MSD and 3,174 LSD cases among children aged
ISSN:	1935-2735 1935-2727 1935-2735
DOI:	10.1371/journal.pntd.0004729