Correlates of Protection against Norovirus Infection and Disease-Where Are We Now, Where Do We Go?

Competing interests: I have read the journal's policy and have the following conflicts: MKE is named as an inventor on patents related to cloning of the Norwalk virus genome and has served as a consultant to Takeda Vaccines, Inc. RLA has received research grant funding from and is an unpaid consultant to Takeda Vaccines, Inc. This does not alter our adherence to all PLOS policies on sharing data and materials. The epidemiology of NoV is complex, with more than 30 genotypes known to cause infections in humans [8]. Since HBGA specificity varies among different NoV genotypes, it is likely that most persons will be susceptible to at least some genotypes [9].