Renal Function in Chinese HIV-Positive Individuals following Initiation of Antiretroviral Therapy

To identify the prevalence and predictors of abnormal renal function among HIV-positive Chinese patients prior to antiretroviral therapy (ART) initiation and to evaluate subsequent changes in renal function after ART exposure. We conducted a nationwide cohort study of subjects who enrolled in the na...

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Veröffentlicht in:PloS one 2015-08, Vol.10 (8), p.e0135462-e0135462
Hauptverfasser: Zhao, Yan, Zhang, Mingjie, Shi, Cynthia X, Zhang, Yao, Cai, Weiping, Zhao, Qingxia, Li, Yong, Li, Huiqin, Liu, Xia, Chen, Limeng, Ma, Ye, Zhang, Fujie, Liu, Zhongfu, Wu, Zunyou
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Sprache:eng
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Zusammenfassung:To identify the prevalence and predictors of abnormal renal function among HIV-positive Chinese patients prior to antiretroviral therapy (ART) initiation and to evaluate subsequent changes in renal function after ART exposure. We conducted a nationwide cohort study of subjects who enrolled in the national Chinese ART program from January 1, 2012 to December 31, 2012. We estimated the glomerular filtration rate (eGFR) of subjects prior to and after initiating ART. Risk factors for abnormal renal function, as defined by eGFR
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0135462