The Curious Road from Basic Pathogen Research to Clinical Translation
[...]when my longtime collaborator Peter Forsyth injected it into human gliomas transplanted into the brains of test immunodeficient mice, the virus grew selectively within the transplanted human brain tumors just like it does in the internal tissues of myxoma-infected rabbits! Since it is totally...
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Veröffentlicht in: | PLoS pathogens 2015-06, Vol.11 (6), p.e1004997-e1004997 |
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Format: | Artikel |
Sprache: | eng |
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[...]when my longtime collaborator Peter Forsyth injected it into human gliomas transplanted into the brains of test immunodeficient mice, the virus grew selectively within the transplanted human brain tumors just like it does in the internal tissues of myxoma-infected rabbits! Since it is totally nonpathogenic for humans, this discovery has convinced us to develop myxoma virus as a new potential therapeutic for a variety of human cancers. |
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ISSN: | 1553-7374 1553-7366 1553-7374 |
DOI: | 10.1371/journal.ppat.1004997 |