It's All about Those Bases: The Need for Incorporating Parasite Genetic Heterogeneity into the Development of Schistosome Vaccines

[...]much of our-omics and empirical investigations of biomolecular host-parasite interaction are based on what could effectively be a genetically limited caricature of the parasite we are trying to prevent. [...]our general lack of understanding about the full extent and distribution of variation throughout the genome, and in the majority of vaccine target regions, is a problem that schistosome researchers have not yet addressed.