Negativation of Trypanosoma cruzi PCR within Six Months after Treatment of a Child with Nifurtimox

Negativation of Trypanosoma cruzi PCR within Six Months after Treatment of a Child with Nifurtimox

  According to recent estimations, there may be as many as 1,500 T. cruzi-infected individuals living in France. The absence of a pediatric formulation increases the risk of under- or overdosing in children. [...]the current development of a dispersible 12.5-mg tablet of benznidazole for the treatme...

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Veröffentlicht in:PLoS neglected tropical diseases 2015-05, Vol.9 (5), p.e0003667-e0003667
Hauptverfasser: Pull, Lauren, Touafek, Feriel, Paris, Luc, Le Loup, Guillaume, Brutus, Laurent, Siriez, Jean-Yves
Format: Artikel
Sprache:eng
Schlagworte:
Antiprotozoan agents
Case studies
Children & youth
Deoxyribonucleic acid
DNA
Dosage and administration
Genetic aspects
Health aspects
Infections
Methods
Noncitizens
Parents & parenting
Patient outcomes
Polymerase chain reaction
Protozoa
Studies
Symposium
Trypanosoma cruzi
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Beschreibung
Zusammenfassung:  According to recent estimations, there may be as many as 1,500 T. cruzi-infected individuals living in France. The absence of a pediatric formulation increases the risk of under- or overdosing in children. [...]the current development of a dispersible 12.5-mg tablet of benznidazole for the treatment of congenitally infected babies is likely to improve dosing accuracy in children.
ISSN:1935-2735
1935-2727
1935-2735
DOI:10.1371/journal.pntd.0003667