Impact of chronic kidney disease on use of evidence-based therapy in stable coronary artery disease: a prospective analysis of 22,272 patients

To assess the frequency of chronic kidney disease (CKD), define the associated demographics, and evaluate its association with use of evidence-based drug therapy in a contemporary global study of patients with stable coronary artery disease. 22,272 patients from the ProspeCtive observational Longitu...

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Veröffentlicht in:	PloS one 2014-07, Vol.9 (7), p.e102335-e102335
Hauptverfasser:	Kalra, Paul R, García-Moll, Xavier, Zamorano, José, Kalra, Philip A, Fox, Kim M, Ford, Ian, Ferrari, Roberto, Tardif, Jean-Claude, Tendera, Michal, Greenlaw, Nicola, Steg, Ph Gabriel
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Angiotensin-converting enzyme inhibitors Angiotensin-Converting Enzyme Inhibitors - therapeutic use Angiotensins Anticholesteremic agents Beta blockers Blood pressure Cardiac arrhythmia Cardiac patients Cardiovascular Agents - therapeutic use Cardiovascular disease Cardiovascular diseases Care and treatment Chronic kidney failure Clinical medicine Clinical trials Comorbidity Coronary artery Coronary artery disease Coronary Artery Disease - drug therapy Coronary vessels Demographics Demography Diabetes Diabetes mellitus Disease prevention Dyslipidemia Embolisms Enzyme inhibitors Enzymes Epidemiology Epidermal growth factor receptors Evidence-Based Medicine Female Glomerular Filtration Rate Health risk assessment Health risks Heart attack Heart attacks Heart diseases Heart failure Heart rate Hospitals Humans Hypertension Kidney diseases Kidneys Male Medical research Medicine and Health Sciences Middle Aged Mortality Myocardial infarction Patients Peptidyl-dipeptidase A Platelet Aggregation Inhibitors - therapeutic use Prevention Prospective Studies Renal Insufficiency, Chronic - physiopathology Risk analysis Risk factors Statins Therapy Treatment Outcome Vascular diseases
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Zusammenfassung:	To assess the frequency of chronic kidney disease (CKD), define the associated demographics, and evaluate its association with use of evidence-based drug therapy in a contemporary global study of patients with stable coronary artery disease. 22,272 patients from the ProspeCtive observational LongitudinAl RegIstry oF patients with stable coronary arterY disease (CLARIFY) were included. Baseline estimated glomerular filtration rate (eGFR) was calculated (CKD-Epidemiology Collaboration formula) and patients categorised according to CKD stage: >89, 60-89, 45-59 and
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0102335