P wave area for quantitative electrocardiographic assessment of left atrial remodeling

Left atrial (LA) dilation provides a substrate for mitral regurgitation (MR) and atrial arrhythmias. ECG can screen for LA dilation but standard approaches do not assess LA geometry as a continuum, as does non-invasive imaging. This study tested ECG-quantified P wave area as an index of LA geometry....

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Veröffentlicht in:	PloS one 2014-06, Vol.9 (6), p.e99178-e99178
Hauptverfasser:	Weinsaft, Jonathan W, Kochav, Jonathan D, Kim, Jiwon, Gurevich, Sergey, Volo, Samuel C, Afroz, Anika, Petashnick, Maya, Kim, Agnes, Devereux, Richard B, Okin, Peter M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Archives & records Arrhythmia Atrial Fibrillation - physiopathology Atrial Remodeling Blood Pressure Cardiac arrhythmia Cardiology Cardiovascular disease Coronary Artery Disease - diagnosis Dilation Echocardiography EKG Electrocardiography Female Fibrillation Flutter Heart Atria - physiopathology Heart attacks Heart failure Humans Magnetic Resonance Imaging Male Medicine Medicine and Health Sciences Middle Aged Mitral Valve Insufficiency - pathology Morphology Patients Regression analysis Regurgitation Risk Severity of Illness Index Substrates
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Zusammenfassung:	Left atrial (LA) dilation provides a substrate for mitral regurgitation (MR) and atrial arrhythmias. ECG can screen for LA dilation but standard approaches do not assess LA geometry as a continuum, as does non-invasive imaging. This study tested ECG-quantified P wave area as an index of LA geometry. 342 patients with CAD underwent ECG and CMR within 7 (0.1±1.4) days. LA area on CMR correlated best with P wave area in ECG lead V1 (r = 0.42, p
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0099178