The outcome of ipsilateral hemihepatectomy in mucin-producing bile duct tumors

Mucin-producing bile duct tumors (MPBTs) are unusual, and we present our experience with nine surgically proven cases. Between November 2002 and November 2012, 9 patients with surgically proven MPBTs (including history of relevant hepatobiliary surgery in 6 patients) were encountered. Their clinical...

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Veröffentlicht in:PloS one 2014-04, Vol.9 (4), p.e92010-e92010
Hauptverfasser: Yang, Xin-wei, Yang, Jue, Li, Liang, Yan, Xing-zhou, Zhang, Bao-hua, Shen, Feng, Wu, Meng-chao
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Sprache:eng
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Zusammenfassung:Mucin-producing bile duct tumors (MPBTs) are unusual, and we present our experience with nine surgically proven cases. Between November 2002 and November 2012, 9 patients with surgically proven MPBTs (including history of relevant hepatobiliary surgery in 6 patients) were encountered. Their clinical, imaging, and surgical findings were reviewed. The most common symptom is intermittent jaundice, which occurs in seven patients. The diagnostic specificity was 77.8% by preoperative Magnetic Resonance Cholangiopancreatography (MRCP). All the patients underwent ipsilateral hemihepatectomy or remnant hemihepatectomy, accompanied caudate lobectomy in one case and concomitant Roux-en-Y choledochojejunostomy in four cases. Postoperative course was uneventful. One patient, who had intra-abdominal recurrence 59 months after surgery, was received reoperation without recurrence at the last follow-up. The remaining eight patients were alive without disease recurrence. Based on our follow up of 9 cases that were surgically treated for MPBTs, we conclude that ipsilateral hemihepatectomy is a safe surgical procedure with an observed recurrence risk of 11.1% and all long-term survival.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0092010