One-year mortality associations in hemodialysis patients after traumatic brain injury--an eight-year population-based study
This study aimed to investigate the one-year mortality associations in hemodialysis patients who underwent neurosurgical intervention after traumatic brain injury (TBI) using a nationwide database in Taiwan. An age- and gender-matched longitudinal cohort study of 4416 subjects, 1104 TBI patients wit...
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Veröffentlicht in: | PloS one 2014-04, Vol.9 (4), p.e93956-e93956 |
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Sprache: | eng |
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Zusammenfassung: | This study aimed to investigate the one-year mortality associations in hemodialysis patients who underwent neurosurgical intervention after traumatic brain injury (TBI) using a nationwide database in Taiwan.
An age- and gender-matched longitudinal cohort study of 4416 subjects, 1104 TBI patients with end-stage renal disease (ESRD) and 3312 TBI patients without ESRD, was conducted using the National Health Insurance Research Database in Taiwan between January 2000 and December 2007. The demographic characteristics, length of stay (LOS), length of ICU stay, length of ventilation (LOV), and tracheostomy were collected and analyzed. The co-morbidities of hypertension (HTN), diabetes mellitus (DM), myocardial infarction (MI), stroke, and heart failure (HF) were also evaluated.
TBI patients with ESRD presented a shorter LOS, a longer length of ICU stay and LOV, and a higher percentage of comorbidities compared with those without ESRD. TBI patients with ESRD displayed a stable trend of one-year mortality rate, 75.82% to 76.79%, from 2000-2007. For TBI patients with ESRD, the median survival time was 0.86 months, and pre-existing stroke was a significant risk factor of mortality (HR: 1.29, 95% C.I.: 1.08-1.55). Pre-existing DM (HR: 1.35, 95% C.I.: 1.12-1.63) and MI (HR: 1.61, 95% C.I.: 1.07-2.42) effect on the mortality in ESRD patients who underwent TBI surgical intervention in the younger (age |
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ISSN: | 1932-6203 1932-6203 |
DOI: | 10.1371/journal.pone.0093956 |