Balancing stability and flexibility within the genome of the pathogen Cryptococcus neoformans

[...]the ascomycete yeast Candida albicans is responsible for the greatest number of fungal infections, particularly those acquired in a hospital setting. [...]the basidiomycete yeast Cryptococcus neoformans has become a scourge of AIDS patients, accounting for an estimated 624,000 deaths per annu...

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Veröffentlicht in:	PLoS pathogens 2013-12, Vol.9 (12), p.e1003764-e1003764
Hauptverfasser:	Ormerod, Kate L, Fraser, James A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Biological - genetics Chromosomes Cryptococcus Cryptococcus neoformans - genetics Cryptococcus neoformans - pathogenicity Evolution, Molecular Genetic aspects Genetic Variation Genome, Fungal Genomes Genomic Instability Genomics Host-Pathogen Interactions - genetics Infections Laboratories Microbial genetics Microbiological research Mortality Mycological Typing Techniques Pearls Pheromones Physiological aspects
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Beschreibung
Zusammenfassung:	[...]the ascomycete yeast Candida albicans is responsible for the greatest number of fungal infections, particularly those acquired in a hospital setting. [...]the basidiomycete yeast Cryptococcus neoformans has become a scourge of AIDS patients, accounting for an estimated 624,000 deaths per annum [2].
ISSN:	1553-7374 1553-7366 1553-7374
DOI:	10.1371/journal.ppat.1003764