Low vitamin D status is associated with nonalcoholic Fatty liver disease independent of visceral obesity in Korean adults

To investigate the association between serum 25-hydroxyvitamin D [25(OH)D] levels and nonalcoholic fatty liver disease (NAFLD) independent of visceral obesity in Koreans and to examine whether the associations differ according to the presence of diabetes or insulin resistance. A total of 1081 adults...

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Veröffentlicht in:PloS one 2013-10, Vol.8 (10), p.e75197-e75197
Hauptverfasser: Seo, Ji A, Eun, Chai Ryoung, Cho, Hyunjoo, Lee, Seung Ku, Yoo, Hye Jin, Kim, Sin Gon, Choi, Kyung Mook, Baik, Sei Hyun, Choi, Dong Seop, Yim, Hyung Joon, Shin, Chol, Kim, Nan Hee
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Sprache:eng
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Zusammenfassung:To investigate the association between serum 25-hydroxyvitamin D [25(OH)D] levels and nonalcoholic fatty liver disease (NAFLD) independent of visceral obesity in Koreans and to examine whether the associations differ according to the presence of diabetes or insulin resistance. A total of 1081 adults were enrolled from a population-based cohort in Ansan city. Serum 25(OH)D concentrations were measured in all subjects. Insulin resistance was measured by homeostasis model assessment of insulin resistance (HOMA-IR). Using computed tomography, NAFLD was diagnosed if the liver attenuation index (LAI, the difference between the mean hepatic and splenic attenuation) was
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0075197