Alterations of Neuromuscular Function after the World's Most Challenging Mountain Ultra-Marathon

We investigated the physiological consequences of the most challenging mountain ultra-marathon (MUM) in the world: a 330-km trail run with 24000 m of positive and negative elevation change. Neuromuscular fatigue (NMF) was assessed before (Pre-), during (Mid-) and after (Post-) the MUM in experienced...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-06, Vol.8 (6), p.e65596-e65596
Hauptverfasser:	Saugy, Jonas, Place, Nicolas, Millet, Guillaume Y, Degache, Francis, Schena, Federico, Millet, Grégoire P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Altitude Biology Blood C-reactive protein Contraction Crack propagation Creatine Creatine kinase Fatigue Fatigue - etiology Fatigue - physiopathology Fatigue failure Humans Inflammation Knee L-Lactate dehydrogenase Lactate dehydrogenase Lactic acid Male Marathons Markers Mathematics Medical research Medicine Middle Aged Muscle Fatigue - physiology Muscles Muscular fatigue Myoglobins Neuromuscular system Pain - etiology Pain - physiopathology Physical Endurance - physiology Physiology Preservation Running Running - physiology Sleep Sleep deprivation Sports medicine Studies Ultramarathon Walking
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	We investigated the physiological consequences of the most challenging mountain ultra-marathon (MUM) in the world: a 330-km trail run with 24000 m of positive and negative elevation change. Neuromuscular fatigue (NMF) was assessed before (Pre-), during (Mid-) and after (Post-) the MUM in experienced ultra-marathon runners (n = 15; finish time = 122.43 hours ±17.21 hours) and in Pre- and Post- in a control group with a similar level of sleep deprivation (n = 8). Blood markers of muscle inflammation and damage were analyzed at Pre- and Post-. Mean ± SD maximal voluntary contraction force declined significantly at Mid- (-13±17% and -10±16%, P
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0065596