Adherence to Antiretroviral Therapy and Its Effect on Survival of HIV-Infected Individuals in Jharkhand, India

Research in India has extensively examined the factors associated with non-adherence to antiretroviral therapy (ART) with limited focus on examining the relationship between adherence to ART regimen and survival status of HIV infected patients. This study examines the effect of optimal adherence to...

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Veröffentlicht in:PloS one 2013-06, Vol.8 (6), p.e66860-e66860
Hauptverfasser: Rai, Sandeep, Mahapatra, Bidhubhusan, Sircar, Subhashish, Raj, Pinnamaneni Yujwal, Venkatesh, Srinivasan, Shaukat, Mohammed, Rewari, Bharat Bhusan
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Sprache:eng
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Zusammenfassung:Research in India has extensively examined the factors associated with non-adherence to antiretroviral therapy (ART) with limited focus on examining the relationship between adherence to ART regimen and survival status of HIV infected patients. This study examines the effect of optimal adherence to ART on survival status of HIV infected patients attending ART centers in Jharkhand, India. Data from a cohort of 239 HIV infected individuals who were initiated ART in 2007 were compiled from medical records retrospectively for 36 months. Socio-demographic characteristics, CD4 T cell count, presence of opportunistic infections at the time of ART initiation and ART regimen intake and survival status was collected periodically. Optimal adherence was assessed using pill count methods; patients who took
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0066860