Multilocus sequence typing (MLST) for characterization of Enterobacter cloacae

Enterobacter cloacae is an important emerging pathogen, which sometime causes respiratory infection, surgical site infection, urinary infection, sepsis, and outbreaks at neonatal units. We have developed a multilocus sequence typing (MLST) scheme utilizing seven housekeeping genes and evaluated the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-06, Vol.8 (6), p.e66358-e66358
Hauptverfasser:	Miyoshi-Akiyama, Tohru, Hayakawa, Kayoko, Ohmagari, Norio, Shimojima, Masahiro, Kirikae, Teruo
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Beta lactamases Bioinformatics Biology Clinical isolates Deoxyribonucleic acid Disease control DNA Drug resistance Enterobacter Enterobacter cloacae Enterobacter cloacae - genetics Epidemics Epidemiology Genetics Genomes Health aspects Hospitals Infection Infections Infectious diseases Laboratories Medicine Methods Multilocus sequence typing Multilocus Sequence Typing - methods Mutation Neonates Outbreaks Performance evaluation Phylogenetics Population growth Sepsis Sheep Statistical analysis Surgery Surgical site infections Urinary tract infections
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Enterobacter cloacae is an important emerging pathogen, which sometime causes respiratory infection, surgical site infection, urinary infection, sepsis, and outbreaks at neonatal units. We have developed a multilocus sequence typing (MLST) scheme utilizing seven housekeeping genes and evaluated the performance in 101 clinical isolates. The MLST scheme yielded 83 sequence types (ST) including 78 novel STs found in the clinical isolates. These findings supported the robustness of the MLST scheme developed in this study.
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0066358