Expanding ART for treatment and prevention of HIV in South Africa: estimated cost and cost-effectiveness 2011-2050

Antiretroviral Treatment (ART) significantly reduces HIV transmission. We conducted a cost-effectiveness analysis of the impact of expanded ART in South Africa. We model a best case scenario of 90% annual HIV testing coverage in adults 15-49 years old and four ART eligibility scenarios: CD4 count

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Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2012-02, Vol.7 (2), p.e30216-e30216
Hauptverfasser:	Granich, Reuben, Kahn, James G, Bennett, Rod, Holmes, Charles B, Garg, Navneet, Serenata, Celicia, Sabin, Miriam Lewis, Makhlouf-Obermeyer, Carla, De Filippo Mack, Christina, Williams, Phoebe, Jones, Louisa, Smyth, Caoimhe, Kutch, Kerry A, Ying-Ru, Lo, Vitoria, Marco, Souteyrand, Yves, Crowley, Siobhan, Korenromp, Eline L, Williams, Brian G
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adults AIDS Anti-HIV Agents - economics Anti-HIV Agents - therapeutic use Antiretroviral agents Antiretroviral drugs CD4 antigen CD4 Lymphocyte Count Cost analysis Cost benefit analysis Cost-Benefit Analysis - trends Costs Costs and Cost Analysis - trends Disease transmission Economic aspects Fatalities Feasibility studies Forecasting Health aspects HIV HIV infections HIV Infections - drug therapy HIV Infections - economics HIV Infections - prevention & control HIV tests Human immunodeficiency virus Humans Impact analysis Infection Infections Medicine Retention Sensitivity Sensitivity analysis South Africa Studies Web sites Websites
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Beschreibung
Zusammenfassung:	Antiretroviral Treatment (ART) significantly reduces HIV transmission. We conducted a cost-effectiveness analysis of the impact of expanded ART in South Africa. We model a best case scenario of 90% annual HIV testing coverage in adults 15-49 years old and four ART eligibility scenarios: CD4 count
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0030216