A prospective study of the causes of febrile illness requiring hospitalization in children in Cambodia

Febrile illnesses are pre-eminent contributors to morbidity and mortality among children in South-East Asia but the causes are poorly understood. We determined the causes of fever in children hospitalised in Siem Reap province, Cambodia. A one-year prospective study of febrile children admitted to A...

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Veröffentlicht in:	PloS one 2013-04, Vol.8 (4), p.e60634-e60634
Hauptverfasser:	Chheng, Kheng, Carter, Michael J, Emary, Kate, Chanpheaktra, Ngoun, Moore, Catrin E, Stoesser, Nicole, Putchhat, Hor, Sona, Soeng, Reaksmey, Sin, Kitsutani, Paul, Sar, Borann, van Doorn, H Rogier, Uyen, Nguyen Hanh, Van Tan, Le, Paris, Daniel H, Paris, Daniel, Blacksell, Stuart D, Amornchai, Premjit, Wuthiekanun, Vanaporn, Parry, Christopher M, Day, Nicholas P J, Kumar, Varun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Antiinfectives and antibacterials Antimicrobial resistance Bacterial Infections - diagnosis Bacterial Infections - epidemiology Burkholderia Cambodia - epidemiology Child Child health Child, Preschool Children Children's hospitals Ciprofloxacin Clinical medicine Comorbidity Coronary artery disease Data processing Demographics Dengue Dengue fever Dengue virus Disease control Drug resistance E coli Encephalitis Fatalities Female Fever Fever - diagnosis Fever - epidemiology Fever - etiology Geography Heart diseases HIV HIV infections Hospitalization Hospitals Human immunodeficiency virus Humans Illnesses Infant Infant, Newborn Infections Infectious diseases Influenza Leptospirosis Male Malnutrition Medical diagnosis Medical research Medical treatment Medicine Melioidosis Microbial drug resistance Morbidity Mortality Multidrug resistance Orientia tsutsugamushi Pediatric diseases Physicians Pneumonia Prospective Studies Public health Regression analysis Risk factors Salmonella Scrub typhus Streptococcus infections Tropical diseases Typhus Undernutrition Vector-borne diseases Viral diseases Virus Diseases - diagnosis Virus Diseases - epidemiology Viruses
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Zusammenfassung:	Febrile illnesses are pre-eminent contributors to morbidity and mortality among children in South-East Asia but the causes are poorly understood. We determined the causes of fever in children hospitalised in Siem Reap province, Cambodia. A one-year prospective study of febrile children admitted to Angkor Hospital for Children, Siem Reap. Demographic, clinical, laboratory and outcome data were comprehensively analysed. Between October 12(th) 2009 and October 12(th) 2010 there were 1225 episodes of febrile illness in 1180 children. Median (IQR) age was 2.0 (0.8-6.4) years, with 850 (69%) episodes in children
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0060634