Analysis of four aberrometers for evaluating lower and higher order aberrations

To compare the measurements of lower and higher order aberrations (HOA) of 4 commonly used aberrometers. Massachusetts Eye & Ear Infirmary, Boston, USA. Prospective, cross-sectional study, in a controlled, single-blinded fashion. Multiple readings were obtained in 42 eyes of 21 healthy volunteers, at a single visit, with each of the following aberrometers: Alcon LADARWave®, Visx WaveScan®, B & L Zywave®, and Wavelight Allegro Analyzer®. Results were compared and analyzed in regards to the lower and HOA, to the different wavefront sensing devices and software, Tscherning and Hartmann-Shack and between the Fourier and Zernike algorithms. Statistical analysis included Bland-Altman plots, Intraclass Correlation Coefficient (ICC), multiple comparison tests with Analysis of Variance and Kruskal-Wallis. Significant level was set to p