The beneficial effects of antifreeze proteins in the vitrification of immature mouse oocytes

Antifreeze proteins (AFPs) are a class of polypeptides that permit organismal survival in sub-freezing environments. The purpose of this study was to investigate the effect of AFP supplementation on immature mouse oocyte vitrification. Germinal vesicle-stage oocytes were vitrified using a two-step e...

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Veröffentlicht in:	PloS one 2012-05, Vol.7 (5), p.e37043
Hauptverfasser:	Jo, Jun Woo, Jee, Byung Chul, Suh, Chang Suk, Kim, Seok Hyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antifreeze proteins Antifreeze Proteins - pharmacology Antigens - genetics Antigens - metabolism Apoptosis Apoptosis - genetics Biology Blastocyst - drug effects Blastomeres Caspase Cell growth Chromosomes DNA Primers - genetics Egg Proteins - genetics Egg Proteins - metabolism Embryogenesis Embryonic development Embryonic Development - drug effects Embryonic growth stage Female Fertility Fertilization Fertilization - drug effects Fertilization - physiology Fluoresceins Freezing Gene expression Gene Expression Regulation, Developmental - drug effects Genes, cdc - genetics Gynecology Integrity Maturation Medicine Membranes Mice Microtubules - genetics Microtubules - metabolism Morphology Obstetrics Oocytes Oocytes - drug effects Oocytes - metabolism Oxidative Stress - genetics Polypeptides Proteins Reverse Transcriptase Polymerase Chain Reaction Spindles Supplementation Supplements Survival Veterinary Science Vitrification Vitrification - drug effects
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