Prolactin secretion in healthy adults is determined by gender, age and body mass index

Prolactin secretion in healthy adults is determined by gender, age and body mass index

Prolactin (PRL) secretion is quantifiable as mean, peak and nadir PRL concentrations, degree of irregularity (ApEn, approximate entropy) and spikiness (brief staccato-like fluctuations). Distinct PRL dynamics reflect relatively distinct (combinations of) subject variables, such as gender, age, and B...

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Veröffentlicht in:PloS one 2012-02, Vol.7 (2), p.e31305-e31305
Hauptverfasser: Roelfsema, Ferdinand, Pijl, Hanno, Keenan, Daniel M, Veldhuis, Johannes D
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Adults
Age
Aged
Aging - physiology
Analysis
Biology
Body mass
Body Mass Index
Chronology
Circadian rhythm
Endocrinology
Entropy
Family medical history
Female
Females
Gender differences
Health
Humans
Hypothyroidism
Linear Models
Male
Medicine
Men
Mens health
Metabolic disorders
Middle Aged
Multivariate analysis
Older people
Plasma
PMS
Postmenopause - blood
Premenopause - blood
Premenstrual syndrome
Prolactin
Prolactin - blood
Prolactin - secretion
Regression analysis
Sex Characteristics
Sleep
Studies
Time Factors
Womens health
Young Adult
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Zusammenfassung:Prolactin (PRL) secretion is quantifiable as mean, peak and nadir PRL concentrations, degree of irregularity (ApEn, approximate entropy) and spikiness (brief staccato-like fluctuations). Distinct PRL dynamics reflect relatively distinct (combinations of) subject variables, such as gender, age, and BMI. Clinical Research Unit. Seventy-four healthy adults aged 22-77 yr (41 women and 33 men), with BMI 18.3-39.4 kg/m(2). Immunofluorometric PRL assay of 10-min samples collected for 24 hours. Mean 24-h PRL concentration correlated jointly with gender (P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0031305