Development of the Respiratory Index of Severity in Children (RISC) score among young children with respiratory infections in South Africa

Pneumonia is a leading cause of death in children worldwide. A simple clinical score predicting the probability of death in a young child with lower respiratory tract infection (LRTI) could aid clinicians in case management and provide a standardized severity measure during epidemiologic studies. We...

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Veröffentlicht in:	PloS one 2012-01, Vol.7 (1), p.e27793-e27793
Hauptverfasser:	Reed, Carrie, Madhi, Shabir A, Klugman, Keith P, Kuwanda, Locadiah, Ortiz, Justin R, Finelli, Lyn, Fry, Alicia M
Format:	Artikel
Sprache:	eng
Schlagworte:	Age AIDS vaccines Analysis Calibration Case management Children Children & youth Clinical medicine Councils Death Disease control Disease prevention Epidemiology Fatalities Female Goodness of fit Health risks HIV HIV Infections - complications HIV Infections - epidemiology Hospitalization Hospitalization - statistics & numerical data Hospitals Human immunodeficiency virus Humans Illnesses Immunization Infant Infant, Newborn Infection Infections Influenza Lung diseases Male Medical research Medicine Mortality Oxygen Oxygen content Pathogens Pediatrics Placebos Pneumococcal Infections - epidemiology Pneumococcal Infections - prevention & control Pneumonia Prognosis Public health Randomized Controlled Trials as Topic Regression analysis Regression models Resampling Research Design Respiratory diseases Respiratory Function Tests - methods Respiratory tract Respiratory tract diseases Respiratory tract infection Respiratory Tract Infections - diagnosis Respiratory Tract Infections - epidemiology Risk analysis Risk factors Saturation Severity of Illness Index South Africa - epidemiology Statistical analysis Systematic review Vaccination Wheezing
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Zusammenfassung:	Pneumonia is a leading cause of death in children worldwide. A simple clinical score predicting the probability of death in a young child with lower respiratory tract infection (LRTI) could aid clinicians in case management and provide a standardized severity measure during epidemiologic studies. We analyzed 4,148 LRTI hospitalizations in children
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0027793