A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

The adipocyte-derived protein adiponectin is highly heritable and inversely associated with risk of type 2 diabetes mellitus (T2D) and coronary heart disease (CHD). We meta-analyzed 3 genome-wide association studies for circulating adiponectin levels (n = 8,531) and sought validation of the lead sin...

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Veröffentlicht in:PLoS genetics 2009-12, Vol.5 (12), p.e1000768-e1000768
Hauptverfasser: Richards, J Brent, Waterworth, Dawn, O'Rahilly, Stephen, Hivert, Marie-France, Loos, Ruth J F, Perry, John R B, Tanaka, Toshiko, Timpson, Nicholas John, Semple, Robert K, Soranzo, Nicole, Song, Kijoung, Rocha, Nuno, Grundberg, Elin, Dupuis, Josée, Florez, Jose C, Langenberg, Claudia, Prokopenko, Inga, Saxena, Richa, Sladek, Robert, Aulchenko, Yurii, Evans, David, Waeber, Gerard, Erdmann, Jeanette, Burnett, Mary-Susan, Sattar, Naveed, Devaney, Joseph, Willenborg, Christina, Hingorani, Aroon, Witteman, Jaquelin C M, Vollenweider, Peter, Glaser, Beate, Hengstenberg, Christian, Ferrucci, Luigi, Melzer, David, Stark, Klaus, Deanfield, John, Winogradow, Janina, Grassl, Martina, Hall, Alistair S, Egan, Josephine M, Thompson, John R, Ricketts, Sally L, König, Inke R, Reinhard, Wibke, Grundy, Scott, Wichmann, H-Erich, Barter, Phil, Mahley, Robert, Kesaniemi, Y Antero, Rader, Daniel J, Reilly, Muredach P, Epstein, Stephen E, Stewart, Alexandre F R, Van Duijn, Cornelia M, Schunkert, Heribert, Burling, Keith, Deloukas, Panos, Pastinen, Tomi, Samani, Nilesh J, McPherson, Ruth, Davey Smith, George, Frayling, Timothy M, Wareham, Nicholas J, Meigs, James B, Mooser, Vincent, Spector, Tim D
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