RecX facilitates homologous recombination by modulating RecA activities

The Bacillus subtilis recH342 strain, which decreases interspecies recombination without significantly affecting the frequency of transformation with homogamic DNA, carried a point mutation in the putative recX (yfhG) gene, and the mutation was renamed as recX342. We show that RecX (264 residues lon...

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Veröffentlicht in:	PLoS genetics 2012-12, Vol.8 (12), p.e1003126-e1003126
Hauptverfasser:	Cárdenas, Paula P, Carrasco, Begoña, Defeu Soufo, Clarisse, César, Carolina E, Herr, Katharina, Kaufenstein, Miriam, Graumann, Peter L, Alonso, Juan C
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus subtilis Bacillus subtilis - genetics Bacterial genetics Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteriology Biology Deoxyribonucleic acid DNA DNA Damage - genetics Genetic aspects Health aspects Homologous Recombination - genetics Homology (Biology) Microbiology Mutation Physiological aspects Point Mutation Rec A Recombinases - genetics Recombinant proteins SOS Response (Genetics) Transformation, Bacterial
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Zusammenfassung:	The Bacillus subtilis recH342 strain, which decreases interspecies recombination without significantly affecting the frequency of transformation with homogamic DNA, carried a point mutation in the putative recX (yfhG) gene, and the mutation was renamed as recX342. We show that RecX (264 residues long), which shares partial identity with the Proteobacterial RecX (
ISSN:	1553-7404 1553-7390 1553-7404
DOI:	10.1371/journal.pgen.1003126