Evidence of a large-scale functional organization of Mammalian chromosomes

Evidence of a large-scale functional organization of Mammalian chromosomes

Applying the Haldane-Waddington equation to these mice for calculating genetic distances is not appropriate, because they were developed from an advanced intercross population with a resulting excess of recombinations.

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Veröffentlicht in:PLoS biology 2007-05, Vol.5 (5), p.e127; author reply e128-e127; author reply e128
Hauptverfasser: Petkov, Petko M, Graber, Joel H, Churchill, Gary A, DiPetrillo, Keith, King, Benjamin L, Paigen, Kenneth
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Chromosomes
Chromosomes, Mammalian - genetics
Correspondence
Genetics
Genome - genetics
Genomes
Genomics
Inbreeding
Mice - genetics
Recombination, Genetic - genetics
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Beschreibung
Zusammenfassung:Applying the Haldane-Waddington equation to these mice for calculating genetic distances is not appropriate, because they were developed from an advanced intercross population with a resulting excess of recombinations.
ISSN:1545-7885
1544-9173
1545-7885
DOI:10.1371/journal.pbio.0050127