Levels of 17β-Estradiol Receptors Expressed in Embryonic and Adult Zebrafish Following In Vivo Treatment of Natural or Synthetic Ligands

The nuclear receptors encompass a group of regulatory proteins involved in a number of physiological processes. The estrogen receptors (ERs), of which one alpha and one beta form exist in mammals function as transcription factors in response to 17β-estradiol (E2). In zebrafish there are three gene p...

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Veröffentlicht in:	PloS one 2010-03, Vol.5 (3), p.e9678
Hauptverfasser:	Chandrasekar, Gayathri, Archer, Amena, Gustafsson, Jan-Åke, Andersson Lendahl, Monika
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Animal tissues Brain Cellular manufacture Danio rerio Developmental Biology/Embryology Diethylstilbestrol Embryogenesis Embryonic growth stage ESR gene Estrogen receptors Estrogens Exposure Eye Fertilization Fish Gene expression Genes Genetics and Genomics/Gene Expression Industrial plants Intestine Kidneys Liver Mimicry Molecular Biology/Transcription Initiation and Activation Nonylphenol Nuclear receptors Oncorhynchus mykiss Organs Physiology/Endocrinology Primers Proteins Receptors Regulatory proteins Ribonucleic acid RNA Sewage Sex hormones Swim bladder Transcription factors Trout Waste treatment Water treatment Water treatment plants Xenoestrogens Xiphophorus maculatus Zebrafish
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Beschreibung
Zusammenfassung:	The nuclear receptors encompass a group of regulatory proteins involved in a number of physiological processes. The estrogen receptors (ERs), of which one alpha and one beta form exist in mammals function as transcription factors in response to 17β-estradiol (E2). In zebrafish there are three gene products of estrogen receptors and they are denoted esr1 (ERalpha), esr2a (ERbeta2) and esr2b (ERbeta1). Total RNA of zebrafish early life stages (
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0009678