Quorum sensing in fungi: Q&A

Tyrosol is regulated by environmental conditions [4], and the QSP1 gene that encodes the Cryptococcal peptide is directly regulated by a signal-regulated DNA-binding regulator [5]. [...]these factors may be more accurately thought of as auto-regulatory molecules rather than pure sensors of culture d...

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Veröffentlicht in:	PLoS pathogens 2011-10, Vol.7 (10), p.e1002301-e1002301
1. Verfasser:	Madhani, Hiten D
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Bacteriology Biofilms Biology Candida albicans - pathogenicity Candida albicans - physiology Cell division Deoxyribonucleic acid DNA Drug resistance Farnesol - metabolism Fixed rates Fungi Fungi - physiology Genes, Fungal Genetics, Microbial Medicine Microbiology Pathogenesis Pearls Peptides Phenylethyl Alcohol - analogs & derivatives Phenylethyl Alcohol - metabolism Proteins Quorum Sensing - genetics Signal transduction Signal Transduction - physiology Virulence Yeast
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Beschreibung
Zusammenfassung:	Tyrosol is regulated by environmental conditions [4], and the QSP1 gene that encodes the Cryptococcal peptide is directly regulated by a signal-regulated DNA-binding regulator [5]. [...]these factors may be more accurately thought of as auto-regulatory molecules rather than pure sensors of culture density. [...]farnesol can inhibit growth, biofilm formation, and virulence factors by some bacteria [14]-[17], which could be relevant for the lifestyle of C. albicans as a human gut commensal.
ISSN:	1553-7374 1553-7366 1553-7374
DOI:	10.1371/journal.ppat.1002301