Malassezia fungi are specialized to live on skin and associated with dandruff, eczema, and other skin diseases

Introduction Malassezia is a monophyletic genus of fungi found on the skin of 7 billion humans and associated with a variety of conditions, including dandruff, atopic eczema (AE)/dermatitis, pityriasis versicolor, seborrheic dermatitis, and folliculitis ([1], [2]; Figure 1). [...]these agents also inhibit fungal calcineurin, and exhibit anti-fungal activity that has been well documented for Malassezia species [35]. [...]the efficacy of these topical agents may stem from a dual action to suppress host immune response and concomitantly inhibit growth of the fungus provoking host immune responses.