Nutritional immunology: a multi-dimensional approach

Diet affects host nutritional state and immune status, both of which interact with microbial symbionts, commensals, and pathogens to affect the fitness of all partners. Because nutrient feedbacks modulate host feeding behaviour, the potential exists for the host to adjust its diet to optimise its mi...

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Veröffentlicht in:PLoS pathogens 2011-12, Vol.7 (12), p.e1002223-e1002223
Hauptverfasser: Ponton, Fleur, Wilson, Kenneth, Cotter, Sheena C, Raubenheimer, David, Simpson, Stephen J
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Sprache:eng
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Zusammenfassung:Diet affects host nutritional state and immune status, both of which interact with microbial symbionts, commensals, and pathogens to affect the fitness of all partners. Because nutrient feedbacks modulate host feeding behaviour, the potential exists for the host to adjust its diet to optimise its microbial interactions and increase resistance to infection. [...]hosts could be offered the opportunity to express nutritional self-medication in experimental designs in which they are offered a choice of nutritionally complementary foods [45].
ISSN:1553-7374
1553-7366
1553-7374
DOI:10.1371/journal.ppat.1002223