Impact of endofungal bacteria on infection biology, food safety, and drug development

[...]surgical debridement of infected tissue is often necessary [11]. [...]related Burkholderia strains have been isolated from clinical specimen [13]. [...]the existence of toxinogenic endosymbionts should be kept in mind when it comes to treatment of zygomycosis.\n Both vertical and horizontal transmission could be shown to be relevant during evolution of the Burkholderia-Rhizopus alliance: comparison of phylogenetic trees of host strains and the corresponding symbiont strains revealed that the topologies of these trees resemble each other [23].