Serotonin and depression: a disconnect between the advertisements and the scientific literature

Many ads for SSRI antidepressants claim that the drugs boost brain serotonin levels. Lacasse and Leo argue there is little scientific evidence to support this claim.

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Bibliographische Detailangaben
Veröffentlicht in:	PLoS medicine 2005-12, Vol.2 (12), p.e392-e392
Hauptverfasser:	Lacasse, Jeffrey R, Leo, Jonathan
Format:	Artikel
Sprache:	eng
Schlagworte:	Advertising Advertising campaigns Antidepressants Antidepressive Agents - therapeutic use Anxiety Disorders (Including Obsessive Compulsive Disorder and Post-Traumatic Stress Disorder) Brain research Clinical trials Community Participation Consumer advertising Depression - drug therapy Depression - physiopathology Drugs and Adverse Drug Reactions Humans Hypotheses Medical research Mental depression Mental disorders Mental Health Mood Disorders (Including Depression) Neurosciences Other Pharmaceutical industry Pharmacology/Drug Discovery Psychiatry R&D Randomized Controlled Trials as Topic Research & development Selective Serotonin Reuptake Inhibitors - therapeutic use Serotonin Serotonin - metabolism Serotonin - physiology Suicides & suicide attempts Television advertising United States United States Food and Drug Administration
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Beschreibung
Zusammenfassung:	Many ads for SSRI antidepressants claim that the drugs boost brain serotonin levels. Lacasse and Leo argue there is little scientific evidence to support this claim.
ISSN:	1549-1676 1549-1277 1549-1676
DOI:	10.1371/journal.pmed.0020392