Synthesis of Melithasterol A, a 5α,6α-Epoxy-7α-hydroxy Δ8-Steroid

A short, first synthesis of melithasterol A (3) utilizing microwave irradiation-induced isomerization of 5α,8α-epidioxy steroid (1) as the key step has been achieved in 80% yield.

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Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 2000-10, Vol.63 (10), p.1420-1421
Hauptverfasser: Ramesh, P, Reddy, V. L. Niranjan, Reddy, N. Srinivasa, Venkateswarlu, Y
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container_end_page 1421
container_issue 10
container_start_page 1420
container_title Journal of natural products (Washington, D.C.)
container_volume 63
creator Ramesh, P
Reddy, V. L. Niranjan
Reddy, N. Srinivasa
Venkateswarlu, Y
description A short, first synthesis of melithasterol A (3) utilizing microwave irradiation-induced isomerization of 5α,8α-epidioxy steroid (1) as the key step has been achieved in 80% yield.
doi_str_mv 10.1021/np000095i
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subjects Alicyclic compounds, terpenoids, prostaglandins, steroids
Chemistry
Exact sciences and technology
Organic chemistry
Preparations and properties
Steroids
title Synthesis of Melithasterol A, a 5α,6α-Epoxy-7α-hydroxy Δ8-Steroid
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