Studies on zinc sulphate microcapsules (1): Microencapsulation and in vitro dissolution kinetics

Studies on zinc sulphate microcapsules (1): Microencapsulation and in vitro dissolution kinetics

Abstract Microcapsules of zinc sulphate with core: wall ratios of 1:1 and 2:1 were prepared by the coacervation method, using ethylcellulose as the coating material. The prepared microcapsules were separated into batches of 250 and 500 μm in size by sieving. The effects of particle size, the amount...

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Veröffentlicht in:Journal of microencapsulation 1988, Vol.5 (3), p.219-223
Hauptverfasser: öner, L., Ka, H. S., Hincal, A. A.
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Capsules
Cellulose - analogs & derivatives
Drug Compounding
General pharmacology
Medical sciences
Pharmaceutical technology. Pharmaceutical industry
Pharmacology. Drug treatments
Solubility
Sulfates - pharmacokinetics
Zinc - pharmacokinetics
Zinc Sulfate
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Zusammenfassung:Abstract Microcapsules of zinc sulphate with core: wall ratios of 1:1 and 2:1 were prepared by the coacervation method, using ethylcellulose as the coating material. The prepared microcapsules were separated into batches of 250 and 500 μm in size by sieving. The effects of particle size, the amount of zinc sulphate, and the core: wall ratio on the dissolution kinetics were studied, and evaluated kinetically by the Rosin-Rammler-Sperling-Bennet-Weillbull (RRSBW) distribution.
ISSN:0265-2048
1464-5246
DOI:10.3109/02652048809064166