Carbocyclic 5-iodo-2'-deoxyuridine (C-IDU) and carbocyclic (E)--(2-bromovinyl)-2'-deoxyuridine (C-BVDU) as unique examples of chiral molecules where the two enantiomeric forms are biologically active : interaction of the (+)-and (-)-enantiomers of C-IDU and C-BVDU with the thymidine kinase of herpes simplex virus type 1

Carbocyclic 5-iodo-2'-deoxyuridine (C-IDU) and carbocyclic (E)--(2-bromovinyl)-2'-deoxyuridine (C-BVDU) as unique examples of chiral molecules where the two enantiomeric forms are biologically active : interaction of the (+)-and (-)-enantiomers of C-IDU and C-BVDU with the thymidine kinase of herpes simplex virus type 1

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Veröffentlicht in:Molecular pharmacology 1990, Vol.37 (3), p.395-401
Hauptverfasser: BALZARINI, J, DE CLERCQ, E, BAUMGARTNER, H, BODENTEICH, M, GRIENGL, H
Format: Artikel
Sprache:eng
Schlagworte:
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiviral agents
Biological and medical sciences
Medical sciences
Pharmacology. Drug treatments
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ISSN:0026-895X
1521-0111